Linker Information
General Information of This Linker
| Linker ID |
LIN0LOMBA
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| Linker Name |
CN110974975B-C-00-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H50N8O10
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| Isosmiles |
CC(C)[C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N(C)CCN(C(O)=O)C)=O)C=C2)=O)=O
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| InChI |
InChI=1S/C34H50N8O10/c1-22(2)29(39-26(43)10-6-5-7-18-42-27(44)15-16-28(42)45)31(47)38-25(9-8-17-36-32(35)48)30(46)37-24-13-11-23(12-14-24)21-52-34(51)41(4)20-19-40(3)33(49)50/h11-16,22,25,29H,5-10,17-21H2,1-4H3,(H,37,46)(H,38,47)(H,39,43)(H,49,50)(H3,35,36,48)/t25-,29-/m0/s1
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| InChIKey |
YKLLRZICFHFFCA-SVEHJYQDSA-N
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| Pharmaceutical Properties |
Molecule Weight
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730.82
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Polar area
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249.88
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Complexity
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1381.989643
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xlogp Value
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1.3628
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Heavy Count
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52
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Rot Bonds
|
21
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker