Linker Information
General Information of This Linker
| Linker ID |
LIN0LOLFU
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| Linker Name |
IG-L-18 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C53H86N6O23S
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCSC[C@H](NC(COCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)C(N[C@@H](C)C(N[C@@H](C)C(NC2=CC=C(COC(O)=O)C=C2)=O)=O)=O
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| InChI |
InChI=1S/C53H86N6O23S/c1-41(50(64)55-42(2)51(65)57-44-6-4-43(5-7-44)38-82-53(67)68)56-52(66)45(58-47(61)39-81-35-34-70-13-11-54-46(60)10-12-59-48(62)8-9-49(59)63)40-83-37-36-80-33-32-79-31-30-78-29-28-77-27-26-76-25-24-75-23-22-74-21-20-73-19-18-72-17-16-71-15-14-69-3/h4-9,41-42,45H,10-40H2,1-3H3,(H,54,60)(H,55,64)(H,56,66)(H,57,65)(H,58,61)(H,67,68)/t41-,42-,45-/m0/s1
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| InChIKey |
DWCJBJJXAAENAI-WRQZLFHVSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1207.357
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Polar area
|
349.4
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Complexity
|
1870.307866
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xlogp Value
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-0.676
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Heavy Count
|
83
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Rot Bonds
|
55
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Hbond acc
|
23
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker