Linker Information
General Information of This Linker
| Linker ID |
LIN0LMERI
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| Linker Name |
CN117362435A+CD44-DRT+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C26H34N6O7
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| Isosmiles |
O=C(N1CCCCCC(NCC(NCC(N[C@H](C(NCC(NC)=O)=O)CC2=CC=CC=C2)=O)=O)=O)C=CC1=O
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| InChI |
InChI=1S/C26H34N6O7/c1-27-21(34)15-30-26(39)19(14-18-8-4-2-5-9-18)31-23(36)17-29-22(35)16-28-20(33)10-6-3-7-13-32-24(37)11-12-25(32)38/h2,4-5,8-9,11-12,19H,3,6-7,10,13-17H2,1H3,(H,27,34)(H,28,33)(H,29,35)(H,30,39)(H,31,36)/t19-/m0/s1
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| InChIKey |
LETKGXXMROUGGW-IBGZPJMESA-N
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| Pharmaceutical Properties |
Molecule Weight
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542.593
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Polar area
|
182.88
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Complexity
|
1022.769067
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xlogp Value
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-1.7061
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Heavy Count
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39
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Rot Bonds
|
16
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Hbond acc
|
7
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker