Linker Information
General Information of This Linker
| Linker ID |
LIN0LGSGX
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|---|---|---|---|---|---|---|
| Linker Name |
BrAc-Ala-Ala
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C8H13BrN2O4
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| Isosmiles |
C[C@H](NC([C@@H](NC(CBr)=O)C)=O)C(O)=O
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| InChI |
InChI=1S/C8H13BrN2O4/c1-4(10-6(12)3-9)7(13)11-5(2)8(14)15/h4-5H,3H2,1-2H3,(H,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1
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| InChIKey |
LSVCWUKTQRTKEW-WHFBIAKZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
281.106
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Polar area
|
95.5
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Complexity
|
244.7639251
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xlogp Value
|
-0.5247
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Heavy Count
|
15
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Rot Bonds
|
5
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Hbond acc
|
3
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker