Linker Information
General Information of This Linker
| Linker ID |
LIN0LGNGH
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| Linker Name |
CN119630431A-ADC-20-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H37N3O8S2
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| Isosmiles |
OC([C@@H](NC(CNC(CCOCCOCCN(C1=O)C(C(C1SC2=CC=CC=C2)SC3=CC=CC=C3)=O)=O)=O)CC4=CC=CC=C4)=O
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| InChI |
InChI=1S/C34H37N3O8S2/c38-28(35-23-29(39)36-27(34(42)43)22-24-10-4-1-5-11-24)16-18-44-20-21-45-19-17-37-32(40)30(46-25-12-6-2-7-13-25)31(33(37)41)47-26-14-8-3-9-15-26/h1-15,27,30-31H,16-23H2,(H,35,38)(H,36,39)(H,42,43)/t27-,30?,31?/m0/s1
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| InChIKey |
ZOSZRQAGTFYUBC-OCHSWLLGSA-N
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| Pharmaceutical Properties |
Molecule Weight
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679.817
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Polar area
|
151.34
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Complexity
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1363.62821
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xlogp Value
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3.0286
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Heavy Count
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47
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Rot Bonds
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19
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Hbond acc
|
9
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker