Linker Information
General Information of This Linker
| Linker ID |
LIN0LGGZZ
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|---|---|---|---|---|---|---|
| Name |
CN113813399A-ADC:LN401-34-3-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H42N6O8
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C=C2)COCO)=O)=O)C
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| InChI |
InChI=1S/C29H42N6O8/c1-19(2)26(34-23(37)8-4-3-5-16-35-24(38)13-14-25(35)39)28(41)33-22(7-6-15-31-29(30)42)27(40)32-21-11-9-20(10-12-21)17-43-18-36/h9-14,19,22,26,36H,3-8,15-18H2,1-2H3,(H,32,40)(H,33,41)(H,34,37)(H3,30,31,42)/t22-,26-/m0/s1
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| InChIKey |
UWHLHBHZYNVMGG-NVQXNPDNSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
602.689
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Polar area
|
209.26
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Complexity
|
1083.197358
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xlogp Value
|
0.651
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Heavy Count
|
43
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Rot Bonds
|
19
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker