Linker Information
General Information of This Linker
| Linker ID |
LIN0LFPTO
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Bis-bromine linker-PEG4-Asn-Ala-ethylenediamine
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C31H46Br2N8O9
|
|||||
| Isosmiles |
CC(NC(=O)C(CC(N)=O)NC(=O)CCOCCOCCOCCOCCNC(=O)c1ccc2nc(CBr)c(CBr)nc2c1)C(=O)NCCN
|
|||||
| InChI |
InChI=1S/C31H46Br2N8O9/c1-20(29(44)36-6-5-34)38-31(46)24(17-27(35)42)41-28(43)4-8-47-10-12-49-14-15-50-13-11-48-9-7-37-30(45)21-2-3-22-23(16-21)40-26(19-33)25(18-32)39-22/h2-3,16,20,24H,4-15,17-19,34H2,1H3,(H2,35,42)(H,36,44)(H,37,45)(H,38,46)(H,41,43)
|
|||||
| InChIKey |
PDQKOKHCBISXDJ-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
834.564
|
Polar area
|
248.21
|
||
|
Complexity
|
50
|
xlogp Value
|
-0.4543
|
|||
|
Heavy Count
|
50
|
Rot Bonds
|
26
|
|||
|
Hbond acc
|
12
|
Hbond Donor
|
6
|
|||
Each Antibody-drug Conjugate Related to This Linker
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.