Linker Information
General Information of This Linker
| Linker ID |
LIN0LAFKI
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| Linker Name |
CN112604004B-SCT-200-C-2-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H45N5O9
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| Isosmiles |
O=C(OCC1=CC=C(C=C1)NC(C(C)NC(C(C(C)C)NC(C(C)NC(CC2CCC(CCN3C(C=CC3=O)=O)CC2)=O)=O)=O)=O)O
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| InChI |
InChI=1S/C33H45N5O9/c1-19(2)29(32(44)35-21(4)30(42)36-25-11-9-24(10-12-25)18-47-33(45)46)37-31(43)20(3)34-26(39)17-23-7-5-22(6-8-23)15-16-38-27(40)13-14-28(38)41/h9-14,19-23,29H,5-8,15-18H2,1-4H3,(H,34,39)(H,35,44)(H,36,42)(H,37,43)(H,45,46)
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| InChIKey |
ZOIPOGXQBHFAPW-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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655.749
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Polar area
|
200.31
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Complexity
|
1279.985459
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xlogp Value
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2.4815
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Heavy Count
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47
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Rot Bonds
|
15
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Hbond acc
|
8
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker