Linker Information
General Information of This Linker
| Linker ID |
LIN0KYPHY
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|---|---|---|---|---|---|---|
| Linker Name |
TWI857167B-IC-70-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C32H50F4O15
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| Isosmiles |
O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC1=C(F)C(F)=CC(F)=C1F)=O
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| InChI |
InChI=1S/C32H50F4O15/c33-26-25-27(34)31(36)32(30(26)35)51-29(39)2-4-41-6-8-43-10-12-45-14-16-47-18-20-49-22-24-50-23-21-48-19-17-46-15-13-44-11-9-42-7-5-40-3-1-28(37)38/h25H,1-24H2,(H,37,38)
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| InChIKey |
RYTPCPVTMSQSJY-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
750.729
|
Polar area
|
165.13
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Complexity
|
936.4906722
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xlogp Value
|
2.1958
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Heavy Count
|
51
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Rot Bonds
|
37
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Hbond acc
|
14
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Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker