Linker Information
General Information of This Linker
| Linker ID |
LIN0KTPKM
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| Linker Name |
Mal-PEG4-VC-PAB-DMEA
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H57N7O14
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| Isosmiles |
CC(C)[C@H](NC(CCOCCOCCOCCOCCNC(CCN1C(CCC1=O)=O)=O)=O)C(N[C@H](CCCNC(N)=O)C(NC2=CC=C(C=C2)COC(O)=O)=O)=O
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| InChI |
InChI=1S/C37H57N7O14/c1-25(2)33(35(50)42-28(4-3-13-40-36(38)51)34(49)41-27-7-5-26(6-8-27)24-58-37(52)53)43-30(46)12-16-54-18-20-56-22-23-57-21-19-55-17-14-39-29(45)11-15-44-31(47)9-10-32(44)48/h5-8,25,28,33H,3-4,9-24H2,1-2H3,(H,39,45)(H,41,49)(H,42,50)(H,43,46)(H,52,53)(H3,38,40,51)/t28-,33+/m1/s1
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| InChIKey |
ZNMJWVVHAAOBLV-YDYNHKSESA-N
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| Pharmaceutical Properties |
Molecule Weight
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823.898
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Polar area
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292.35
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Complexity
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1404.418002
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xlogp Value
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0.0056
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Heavy Count
|
58
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Rot Bonds
|
30
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Hbond acc
|
13
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker