Linker Information
General Information of This Linker
| Linker ID |
LIN0KSNVQ
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| Linker Name |
MC-Ala-Ala-RG-4
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H48N6O9
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| Isosmiles |
O=C(N[C@@H](C)C(NC1=CC=C(COC(NC(C)C2=C(C)C=CC=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C37H48N6O9/c1-22(2)33(41-29(44)13-8-7-9-20-43-30(45)18-19-31(43)46)35(48)38-25(5)34(47)40-27-16-14-26(15-17-27)21-52-36(49)39-24(4)32-23(3)11-10-12-28(32)42(6)37(50)51/h10-12,14-19,22,24-25,33H,7-9,13,20-21H2,1-6H3,(H,38,48)(H,39,49)(H,40,47)(H,41,44)(H,50,51)/t24?,25-,33-/m0/s1
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| InChIKey |
RBORWTVKGDSEPZ-COYROPBISA-N
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| Pharmaceutical Properties |
Molecule Weight
|
720.824
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Polar area
|
203.55
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Complexity
|
1596.231551
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xlogp Value
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4.16602
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Heavy Count
|
52
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Rot Bonds
|
17
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Hbond acc
|
8
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker