Linker Information
General Information of This Linker
| Linker ID |
LIN0KQUGY
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| Linker Name |
CN119630431A-ADC-83-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C38H41N5O10S2
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| Isosmiles |
OC(CNC([C@@H](NC(CNC(CNC(CCOCCOCCN(C1=O)C(C(SC2=CC=CC=C2)=C1SC3=CC=CC=C3)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O
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| InChI |
InChI=1S/C38H41N5O10S2/c44-30(39-23-31(45)40-24-32(46)42-29(36(49)41-25-33(47)48)22-26-10-4-1-5-11-26)16-18-52-20-21-53-19-17-43-37(50)34(54-27-12-6-2-7-13-27)35(38(43)51)55-28-14-8-3-9-15-28/h1-15,29H,16-25H2,(H,39,44)(H,40,45)(H,41,49)(H,42,46)(H,47,48)/t29-/m0/s1
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| InChIKey |
PZQNOOMVAXZTAU-LJAQVGFWSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
791.905
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Polar area
|
209.54
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Complexity
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1695.609672
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xlogp Value
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1.7354
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Heavy Count
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55
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Rot Bonds
|
23
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Hbond acc
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11
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker