Linker Information
General Information of This Linker
| Linker ID |
LIN0KQPHW
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| Linker Name |
ADCProductionexampleNo.16Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C62H101N11O30P2
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| Isosmiles |
CC([C@H](NC([C@@H](NC(CCOCCOCCOCCOCCNC([C@@H](N1C(C=CC1=O)=O)CNC(CCOCCOCCOCCOCCOCCC(NCCCC(O)(P(O)(O)=O)P(O)(O)=O)=O)=O)=O)=O)CC(N[C@@H](CCO2)C2=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC3=CC=C(C=C3)CO)=O)=O)C
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| InChI |
InChI=1S/C62H101N11O30P2/c1-42(2)55(59(84)71-45(5-3-17-66-61(63)86)56(81)68-44-8-6-43(41-74)7-9-44)72-57(82)47(39-52(78)69-46-12-23-103-60(46)85)70-51(77)15-22-96-27-31-100-33-36-101-32-28-97-24-19-65-58(83)48(73-53(79)10-11-54(73)80)40-67-50(76)14-21-95-26-30-99-35-38-102-37-34-98-29-25-94-20-13-49(75)64-18-4-16-62(87,104(88,89)90)105(91,92)93/h6-11,42,45-48,55,74,87H,3-5,12-41H2,1-2H3,(H,64,75)(H,65,83)(H,67,76)(H,68,81)(H,69,78)(H,70,77)(H,71,84)(H,72,82)(H3,63,66,86)(H2,88,89,90)(H2,91,92,93)/t45-,46-,47-,48-,55-/m0/s1
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| InChIKey |
RSJPPWZSJYISKX-JNPRNYESSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1542.485
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Polar area
|
590.19
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Complexity
|
2863.319723
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xlogp Value
|
-4.7583
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Heavy Count
|
105
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Rot Bonds
|
59
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Hbond acc
|
26
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Hbond Donor
|
16
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Each Antibody-drug Conjugate Related to This Linker