General Information of This Linker
Linker ID
LIN0KPPZE
Linker Name
CN106714844B-ADC-135-linker
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C8H11N3O2S2
Isosmiles
C[C@H](SSC1=NC=C([N+]([O-])=O)C=C1)CN
InChI
InChI=1S/C8H11N3O2S2/c1-6(4-9)14-15-8-3-2-7(5-10-8)11(12)13/h2-3,5-6H,4,9H2,1H3/t6-/m0/s1
InChIKey
CLQIYJQJWCUVJQ-LURJTMIESA-N
Pharmaceutical Properties
Molecule Weight
245.329
Polar area
82.05
Complexity
305.3151247
xlogp Value
2.0773
Heavy Count
15
Rot Bonds
5
Hbond acc
6
Hbond Donor
1
Each Antibody-drug Conjugate Related to This Linker