Linker Information
General Information of This Linker
| Linker ID |
LIN0KNQWV
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|---|---|---|---|---|---|---|
| Linker Name |
Mc-PEG3-Val-Cit
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H39N5O10
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| Isosmiles |
CC(C)[C@H](NC(=O)CCOCCOCCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](CCCNC(N)=O)C(=O)O
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| InChI |
InChI=1S/C24H39N5O10/c1-16(2)21(22(33)27-17(23(34)35)4-3-8-26-24(25)36)28-18(30)7-10-37-12-14-39-15-13-38-11-9-29-19(31)5-6-20(29)32/h5-6,16-17,21H,3-4,7-15H2,1-2H3,(H,27,33)(H,28,30)(H,34,35)(H3,25,26,36)/t17-,21-/m0/s1
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| InChIKey |
LZNRSLMUWFJSGR-UWJYYQICSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
557.601
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Polar area
|
215.69
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Complexity
|
557.2696924
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xlogp Value
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-1.49
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Heavy Count
|
39
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Rot Bonds
|
21
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Hbond acc
|
9
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker