Linker Information
General Information of This Linker
| Linker ID |
LIN0KNCSF
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| Linker Name |
CN119630431A-ADC-44-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C31H35N5O10S2
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| Isosmiles |
O=C(N)C[C@H](NC([C@@H](NC(CCOCCOCCN1C(C(SC2=CC=CC=C2)=C(SC3=CC=CC=C3)C1=O)=O)=O)CC(N)=O)=O)C(O)=O
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| InChI |
InChI=1S/C31H35N5O10S2/c32-23(37)17-21(28(40)35-22(31(43)44)18-24(33)38)34-25(39)11-13-45-15-16-46-14-12-36-29(41)26(47-19-7-3-1-4-8-19)27(30(36)42)48-20-9-5-2-6-10-20/h1-10,21-22H,11-18H2,(H2,32,37)(H2,33,38)(H,34,39)(H,35,40)(H,43,44)/t21-,22-/m0/s1
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| InChIKey |
CZOCPXQQNLETPN-VXKWHMMOSA-N
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| Pharmaceutical Properties |
Molecule Weight
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701.78
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Polar area
|
237.52
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Complexity
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1392.896425
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xlogp Value
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0.3797
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Heavy Count
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48
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Rot Bonds
|
21
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Hbond acc
|
11
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker