Linker Information
General Information of This Linker
| Linker ID |
LIN0KKWJH
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|---|---|---|---|---|---|---|
| Linker Name |
Mal-ValCitGlyPro-OH
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H37N7O9
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| Isosmiles |
CC(C)[C@H](NC(CCN1C(C=CC1=O)=O)=O)C(N[C@H](C(NCC(N2[C@@H](CCC2)C(O)=O)=O)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C25H37N7O9/c1-14(2)21(30-17(33)9-12-32-18(34)7-8-19(32)35)23(38)29-15(5-3-10-27-25(26)41)22(37)28-13-20(36)31-11-4-6-16(31)24(39)40/h7-8,14-16,21H,3-6,9-13H2,1-2H3,(H,28,37)(H,29,38)(H,30,33)(H,39,40)(H3,26,27,41)/t15-,16-,21-/m0/s1
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| InChIKey |
OHJUGPFNPICLGG-QYWGDWMGSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
579.611
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Polar area
|
237.41
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Complexity
|
1017.909327
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xlogp Value
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-2.4326
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Heavy Count
|
41
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Rot Bonds
|
15
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker