Linker Information
General Information of This Linker
| Linker ID |
LIN0KJZYZ
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
Linker of ADC2-39
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C24H30N6O10S
|
|||||
| Isosmiles |
O=C(NCC(NCCC(NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(O)=O)=O)=O)=O)=O)=O)/C=C\C(O)=O.[S]
|
|||||
| InChI |
InChI=1S/C24H30N6O10.S/c31-17(6-7-22(36)37)26-11-19(33)25-9-8-18(32)27-12-20(34)28-13-21(35)30-16(24(40)29-14-23(38)39)10-15-4-2-1-3-5-15;/h1-7,16H,8-14H2,(H,25,33)(H,26,31)(H,27,32)(H,28,34)(H,29,40)(H,30,35)(H,36,37)(H,38,39);/b7-6-;/t16-;/m0./s1
|
|||||
| InChIKey |
FVJHWUCXAGHTPQ-IHNVFOHHSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
594.603
|
Polar area
|
249.2
|
||
|
Complexity
|
1068.294887
|
xlogp Value
|
-2.9414
|
|||
|
Heavy Count
|
41
|
Rot Bonds
|
17
|
|||
|
Hbond acc
|
8
|
Hbond Donor
|
8
|
|||
Each Antibody-drug Conjugate Related to This Linker