Linker Information
General Information of This Linker
| Linker ID |
LIN0KJFMD
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| Linker Name |
BrAc-Gly-Glu
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C9H13BrN2O6
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| Isosmiles |
O=C(N[C@H](C(O)=O)CCC(O)=O)C([H])NC(CBr)=O
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| InChI |
InChI=1S/C9H13BrN2O6/c10-3-6(13)11-4-7(14)12-5(9(17)18)1-2-8(15)16/h5H,1-4H2,(H,11,13)(H,12,14)(H,15,16)(H,17,18)/t5-/m0/s1
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| InChIKey |
LLODMEXPRFSSOV-YFKPBYRVSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
325.115
|
Polar area
|
132.8
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Complexity
|
316.9300119
|
xlogp Value
|
-1.0683
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Heavy Count
|
18
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Rot Bonds
|
8
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Hbond acc
|
4
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker