Linker Information
General Information of This Linker
| Linker ID |
LIN0KIJFA
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| Linker Name |
MP-Ala-Ala-RG-9
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H31FO6
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| Isosmiles |
C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(C=C[C@@]43C)=O)[C@@H]1C[C@@H]5[C@@]2(C(CO)=O)OC(C)(C)O5
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| PubChem CID | ||||||
| InChI |
InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1
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| InChIKey |
YNDXUCZADRHECN-JNQJZLCISA-N
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| Pharmaceutical Properties |
Molecule Weight
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434.504
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Polar area
|
93.06
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Complexity
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896.9990981
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xlogp Value
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2.4188
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Heavy Count
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31
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Rot Bonds
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2
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Hbond acc
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6
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker