Linker Information
General Information of This Linker
| Linker ID |
LIN0KHWKI
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|---|---|---|---|---|---|---|
| Linker Name |
M-Gly-Ala-Ala
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C12H15N3O6
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| Isosmiles |
C[C@H](NC([C@@H](NC(CN1C(C=CC1=O)=O)=O)C)=O)C(O)=O
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| InChI |
InChI=1S/C12H15N3O6/c1-6(11(19)14-7(2)12(20)21)13-8(16)5-15-9(17)3-4-10(15)18/h3-4,6-7H,5H2,1-2H3,(H,13,16)(H,14,19)(H,20,21)/t6-,7-/m0/s1
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| InChIKey |
WJGCZEDYDQCTFZ-BQBZGAKWSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
297.267
|
Polar area
|
132.88
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Complexity
|
480.1313521
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xlogp Value
|
-1.9946
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Heavy Count
|
21
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Rot Bonds
|
6
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Hbond acc
|
5
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker