Linker Information
General Information of This Linker
| Linker ID |
LIN0KHEPM
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| Linker Name |
L3-P1 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C70H115N13O28
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| Isosmiles |
CC([C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C(CN(CC3=CN(N=N3)CCOCCOCCOCCOCCOCCOCCOCCOC)C(OCC(N=N4)=CN4CCOCCOCCOCCOCCOCCOCCOCCOC)=O)=C2)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C70H115N13O28/c1-55(2)65(75-62(84)11-16-95-19-15-83-63(85)9-10-64(83)86)67(88)74-61(6-5-12-72-68(71)89)66(87)73-58-8-7-56(53-111-70(91)92)57(48-58)49-80(50-59-51-81(78-76-59)13-17-96-24-26-100-32-34-104-40-42-108-46-44-106-38-36-102-30-28-98-22-20-93-3)69(90)110-54-60-52-82(79-77-60)14-18-97-25-27-101-33-35-105-41-43-109-47-45-107-39-37-103-31-29-99-23-21-94-4/h7-10,48,51-52,55,61,65H,5-6,11-47,49-50,53-54H2,1-4H3,(H,73,87)(H,74,88)(H,75,84)(H,91,92)(H3,71,72,89)/t61-,65-/m0/s1
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| InChIKey |
WZMNKERXCWQNMX-FRTGRWMLSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1586.753
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Polar area
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474.2
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Complexity
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2901.177129
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xlogp Value
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0.2727
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Heavy Count
|
111
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Rot Bonds
|
72
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Hbond acc
|
33
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker