Linker Information
General Information of This Linker
| Linker ID |
LIN0KDPCU
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| Linker Name |
IG-L-3 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C20H24N4O6
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| Isosmiles |
C[C@@H](C(N[C@H](C(NC1=CC=C(CO)C=C1)=O)C)=O)NC(CCN2C(C=CC2=O)=O)=O
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| InChI |
InChI=1S/C20H24N4O6/c1-12(21-16(26)9-10-24-17(27)7-8-18(24)28)19(29)22-13(2)20(30)23-15-5-3-14(11-25)4-6-15/h3-8,12-13,25H,9-11H2,1-2H3,(H,21,26)(H,22,29)(H,23,30)/t12-,13-/m0/s1
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| InChIKey |
CMKUVUSGEFKDLV-STQMWFEESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
416.434
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Polar area
|
144.91
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Complexity
|
809.2942158
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xlogp Value
|
-0.5581
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Heavy Count
|
30
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Rot Bonds
|
9
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Hbond acc
|
6
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker