Linker Information
General Information of This Linker
| Linker ID |
LIN0JZRPQ
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| Linker Name |
TW202506738A-C-066-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H44N4O15
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| Isosmiles |
COCOCOCOCOCOCOCOCCNC(CCC(NC(CCCN1C(C=CC1=O)=O)=O)C(NCCCC(O)=O)=O)=O
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| InChI |
InChI=1S/C27H44N4O15/c1-39-14-41-16-43-18-45-20-46-19-44-17-42-15-40-13-11-28-22(32)7-6-21(27(38)29-10-2-5-26(36)37)30-23(33)4-3-12-31-24(34)8-9-25(31)35/h8-9,21H,2-7,10-20H2,1H3,(H,28,32)(H,29,38)(H,30,33)(H,36,37)
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| InChIKey |
ILOWUZIGTMFUSN-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
664.662
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Polar area
|
235.82
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Complexity
|
888.3228036
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xlogp Value
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-1.4811
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Heavy Count
|
46
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Rot Bonds
|
30
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Hbond acc
|
14
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker