Linker Information
General Information of This Linker
| Linker ID |
LIN0JZQIM
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| Linker Name |
Trastuzumab-LD3-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H44N6O7
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| Isosmiles |
CN(C(OCC1=CC=C(NC([C@@H](NC([C@@H](N(C)C)C(C)C)=O)C)=O)C=C1)=O)CCNCCOCCN2C(C=CC2=O)=O
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| InChI |
InChI=1S/C29H44N6O7/c1-20(2)26(33(4)5)28(39)31-21(3)27(38)32-23-9-7-22(8-10-23)19-42-29(40)34(6)15-13-30-14-17-41-18-16-35-24(36)11-12-25(35)37/h7-12,20-21,26,30H,13-19H2,1-6H3,(H,31,39)(H,32,38)/t21-,26-/m0/s1
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| InChIKey |
RPHPGXSYIPTEJS-LVXARBLLSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
588.706
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Polar area
|
149.62
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Complexity
|
1029.760458
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xlogp Value
|
0.8156
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Heavy Count
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42
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Rot Bonds
|
17
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Hbond acc
|
9
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker