Linker Information
General Information of This Linker
| Linker ID |
LIN0JZFVN
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| Linker Name |
COT-PEG4-VK-PABC
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C48H81N9O15
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| Isosmiles |
CC([C@H](NC(CCOCCOCCOCCOCCNC(COC1C(N=NN2CCOCCOCCOCCN)=C2CCCCC1)=O)=O)C(N[C@@H](CCCCN)C(NC3=CC=C(C=C3)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C48H81N9O15/c1-36(2)44(47(61)53-39(8-6-7-16-49)46(60)52-38-13-11-37(12-14-38)34-72-48(62)63)54-42(58)15-20-64-24-28-68-32-33-70-30-26-66-22-18-51-43(59)35-71-41-10-5-3-4-9-40-45(41)55-56-57(40)19-23-67-27-31-69-29-25-65-21-17-50/h11-14,36,39,41,44H,3-10,15-35,49-50H2,1-2H3,(H,51,59)(H,52,60)(H,53,61)(H,54,58)(H,62,63)/t39-,41?,44-/m0/s1
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| InChIKey |
WVFLJXABJYVSNG-QLXUEJMESA-N
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| Pharmaceutical Properties |
Molecule Weight
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1024.224
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Polar area
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319.52
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Complexity
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1718.746451
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xlogp Value
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1.6214
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Heavy Count
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72
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Rot Bonds
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41
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Hbond acc
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19
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Hbond Donor
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7
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Each Antibody-drug Conjugate Related to This Linker