Linker Information
General Information of This Linker
| Linker ID |
LIN0JYZNK
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| Linker Name |
Daratumumab-I-1-1 linker
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| Linker Type |
Uncleavable linker
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| Antibody-Linker Relation |
Uncleavable
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| Structure |
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| Formula |
C40H52F2N6O12S
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| Isosmiles |
COC1=CC=C(NC(C2=CN3C=CSC3=N2)=O)C=C1C(NCCCC(NCC4=CC(F)=C(OC(CCOCCOCCOCCOCCOCCOCCN)=O)C(F)=C4)=O)=O
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| InChI |
InChI=1S/C40H52F2N6O12S/c1-53-34-5-4-29(46-39(52)33-27-48-9-22-61-40(48)47-33)25-30(34)38(51)44-8-2-3-35(49)45-26-28-23-31(41)37(32(42)24-28)60-36(50)6-10-54-12-14-56-16-18-58-20-21-59-19-17-57-15-13-55-11-7-43/h4-5,9,22-25,27H,2-3,6-8,10-21,26,43H2,1H3,(H,44,51)(H,45,49)(H,46,52)
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| InChIKey |
BRKHDBUYIPSRAC-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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878.949
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Polar area
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221.53
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Complexity
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1843.103742
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xlogp Value
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3.1151
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Heavy Count
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61
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Rot Bonds
|
31
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Hbond acc
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16
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker