Linker Information
General Information of This Linker
| Linker ID |
LIN0JXZCQ
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
CN112604004B-SCT-200-M-3-linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C33H40N6O9
|
|||||
| Isosmiles |
O=C(OCC1=CC=C(C=C1)NC(C(NC(C(NC(CC2=CC=C(CCN3C(C=CC3=O)=O)C=C2)=O)C(C)C)=O)CCCNC(N)=O)=O)O
|
|||||
| InChI |
InChI=1S/C33H40N6O9/c1-20(2)29(38-26(40)18-22-7-5-21(6-8-22)15-17-39-27(41)13-14-28(39)42)31(44)37-25(4-3-16-35-32(34)45)30(43)36-24-11-9-23(10-12-24)19-48-33(46)47/h5-14,20,25,29H,3-4,15-19H2,1-2H3,(H,36,43)(H,37,44)(H,38,40)(H,46,47)(H3,34,35,45)
|
|||||
| InChIKey |
FIVUPSQPXCCTMD-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
664.716
|
Polar area
|
226.33
|
||
|
Complexity
|
1447.437811
|
xlogp Value
|
1.604
|
|||
|
Heavy Count
|
48
|
Rot Bonds
|
17
|
|||
|
Hbond acc
|
8
|
Hbond Donor
|
6
|
|||
Each Antibody-drug Conjugate Related to This Linker