Linker Information
General Information of This Linker
| Linker ID |
LIN0JXIPU
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| Linker Name |
TWI857167B-IC-66-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H44F4O14
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| Isosmiles |
O=C(OC1=C(F)C(F)=CC(F)=C1F)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(O)=O
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| InChI |
InChI=1S/C29H44F4O14/c30-23-21-24(31)28(33)29(27(23)32)47-26(36)1-2-37-3-4-38-5-6-39-7-8-40-9-10-41-11-12-42-13-14-43-15-16-44-17-18-45-19-20-46-22-25(34)35/h21H,1-20,22H2,(H,34,35)
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| InChIKey |
VZFHUGZKKUAPOU-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
692.649
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Polar area
|
155.9
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Complexity
|
874.8536596
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xlogp Value
|
1.7891
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Heavy Count
|
47
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Rot Bonds
|
33
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Hbond acc
|
13
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Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker