Linker Information
General Information of This Linker
| Linker ID |
LIN0JLSIA
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|---|---|---|---|---|---|---|
| Linker Name |
B-1 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C31H46N6O9
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| Isosmiles |
CC([C@H](NC(CCOCCCCCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(O)C=C2)=O)=O)C
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| InChI |
InChI=1S/C31H46N6O9/c1-21(2)28(30(43)35-24(7-6-15-33-31(32)44)29(42)34-22-8-10-23(38)11-9-22)36-25(39)14-19-45-17-4-3-5-18-46-20-16-37-26(40)12-13-27(37)41/h8-13,21,24,28,38H,3-7,14-20H2,1-2H3,(H,34,42)(H,35,43)(H,36,39)(H3,32,33,44)/t24-,28-/m0/s1
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| InChIKey |
VLMZGAHOYVDHBY-CUBQBAPOSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
646.742
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Polar area
|
218.49
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Complexity
|
1130.923654
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xlogp Value
|
0.9234
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Heavy Count
|
46
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Rot Bonds
|
22
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker