Linker Information
General Information of This Linker
| Linker ID |
LIN0JHHZC
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| Linker Name |
CN119630431A-ADC-18-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H41N5O8S2
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| Isosmiles |
O=C(N1CCOCCOCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)=O)=O)C(C(SC3=CC=CC=C3)C1=O)SC4=CC=CC=C4
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| InChI |
InChI=1S/C36H41N5O8S2/c37-34(45)28(22-25-10-4-1-5-11-25)40-31(44)24-39-30(43)23-38-29(42)16-18-48-20-21-49-19-17-41-35(46)32(50-26-12-6-2-7-13-26)33(36(41)47)51-27-14-8-3-9-15-27/h1-15,28,32-33H,16-24H2,(H2,37,45)(H,38,42)(H,39,43)(H,40,44)/t28-,32?,33?/m0/s1
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| InChIKey |
XDROLLHJGFUIKQ-BKSDJDGUSA-N
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| Pharmaceutical Properties |
Molecule Weight
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735.885
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Polar area
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186.23
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Complexity
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1492.484165
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xlogp Value
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1.5455
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Heavy Count
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51
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Rot Bonds
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21
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Hbond acc
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10
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Hbond Donor
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4
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Each Antibody-drug Conjugate Related to This Linker