Linker Information
General Information of This Linker
| Linker ID |
LIN0JCSUB
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| Linker Name |
CN116137818A-AbT-EXP6-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H37N6NaO13S
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| Isosmiles |
CC([C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC(S(=O)([O-])=O)=C(C=C2)COC(O)=O)=O)=O)C.[Na+]
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| InChI |
InChI=1S/C28H38N6O13S.Na/c1-16(2)24(33-21(35)9-12-46-13-11-34-22(36)7-8-23(34)37)26(39)32-19(4-3-10-30-27(29)40)25(38)31-18-6-5-17(15-47-28(41)42)20(14-18)48(43,44)45;/h5-8,14,16,19,24H,3-4,9-13,15H2,1-2H3,(H,31,38)(H,32,39)(H,33,35)(H,41,42)(H3,29,30,40)(H,43,44,45);/q;+1/p-1/t19-,24-;/m0./s1
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| InChIKey |
NDDDUIYINKWYIN-RIAYWLAYSA-M
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| Pharmaceutical Properties |
Molecule Weight
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720.69
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Polar area
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292.76
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Complexity
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1441.354991
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xlogp Value
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-3.8664
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Heavy Count
|
49
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Rot Bonds
|
19
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Hbond acc
|
12
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker