Linker Information
General Information of This Linker
| Linker ID |
LIN0JBZLT
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| Linker Name |
CN119630431A-ADC-49-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H33N3O10S2
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| Isosmiles |
O=C(O)C[C@H](NC(CCNC(CCOCCOCCN1C(C(SC2=CC=CC=C2)=C(SC3=CC=CC=C3)C1=O)=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C30H33N3O10S2/c34-23(31-13-11-24(35)32-22(30(40)41)19-25(36)37)12-15-42-17-18-43-16-14-33-28(38)26(44-20-7-3-1-4-8-20)27(29(33)39)45-21-9-5-2-6-10-21/h1-10,22H,11-19H2,(H,31,34)(H,32,35)(H,36,37)(H,40,41)/t22-/m0/s1
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| InChIKey |
PMAIRBYUEGEVLF-QFIPXVFZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
659.739
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Polar area
|
188.64
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Complexity
|
1265.421848
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xlogp Value
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2.1251
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Heavy Count
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45
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Rot Bonds
|
20
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Hbond acc
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10
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker