Linker Information
General Information of This Linker
| Linker ID |
LIN0JBMWN
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| Linker Name |
CN116137818A-AbTTG-EXP8-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H41N8O13S-
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| Isosmiles |
CC([C@H](NC(COCCOCCOCCN=[N+]=[N-])=O)C(N[C@@H](CCCNC(N)=O)C(NC1=CC(S(=O)([O-])=O)=C(C=C1)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C27H42N8O13S/c1-17(2)23(34-22(36)16-47-13-12-46-11-10-45-9-8-31-35-29)25(38)33-20(4-3-7-30-26(28)39)24(37)32-19-6-5-18(15-48-27(40)41)21(14-19)49(42,43)44/h5-6,14,17,20,23H,3-4,7-13,15-16H2,1-2H3,(H,32,37)(H,33,38)(H,34,36)(H,40,41)(H3,28,30,39)(H,42,43,44)/p-1/t20-,23-/m0/s1
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| InChIKey |
SNLIYTGWTBMLRI-REWPJTCUSA-M
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| Pharmaceutical Properties |
Molecule Weight
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717.735
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Polar area
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322.6
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Complexity
|
1346.359864
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xlogp Value
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0.158
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Heavy Count
|
49
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Rot Bonds
|
24
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Hbond acc
|
13
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker