Linker Information
General Information of This Linker
| Linker ID |
LIN0JBABP
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| Linker Name |
CN110997009B ADC#42 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C59H94Br2N6O20
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| Isosmiles |
BrCC1=NC2=CC=C(C(NCCOCCOCCC(N[C@@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(NC3=CC=C(C=C3)CO)=O)=O)=O)C=C2N=C1CBr
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| InChI |
InChI=1S/C59H94Br2N6O20/c1-73-18-19-77-24-25-79-28-29-81-32-33-83-36-37-85-40-41-87-43-42-86-39-38-84-35-34-82-31-30-80-27-26-78-23-21-74-15-11-56(69)62-13-3-2-4-52(59(72)64-50-8-5-48(47-68)6-9-50)67-57(70)12-16-75-20-22-76-17-14-63-58(71)49-7-10-51-53(44-49)66-55(46-61)54(45-60)65-51/h5-10,44,52,68H,2-4,11-43,45-47H2,1H3,(H,62,69)(H,63,71)(H,64,72)(H,67,70)/t52-/m0/s1
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| InChIKey |
ITISVKVTVPZOLX-MPLRIKRWSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1367.231
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Polar area
|
300.86
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Complexity
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2106.8602
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xlogp Value
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3.7107
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Heavy Count
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87
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Rot Bonds
|
60
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Hbond acc
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22
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker