Linker Information
General Information of This Linker
| Linker ID |
LIN0IYBNA
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| Linker Name |
CN113549127A-ADC-18-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C41H71N9O17S
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| Isosmiles |
CC(C)[C@H](NC(OCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCNC(C1=CN=C(S)N=C1)=O)=O)=O)=O)C(N[C@H](C(O)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C41H71N9O17S/c1-30(2)35(37(54)49-32(38(55)56)5-3-8-46-39(42)57)50-41(58)67-29-34(52)44-10-12-60-14-16-62-18-20-64-22-24-66-26-25-65-23-21-63-19-17-61-15-13-59-11-9-43-33(51)6-4-7-45-36(53)31-27-47-40(68)48-28-31/h27-28,30,32,35H,3-26,29H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,49,54)(H,50,58)(H,55,56)(H3,42,46,57)(H,47,48,68)/t32-,35-/m0/s1
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| InChIKey |
IRGWURDWRQIXNZ-SHUZPENHSA-N
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| Pharmaceutical Properties |
Molecule Weight
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994.132
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Polar area
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346.77
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Complexity
|
1473.859879
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xlogp Value
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-1.5908
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Heavy Count
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68
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Rot Bonds
|
43
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Hbond acc
|
19
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker