Linker Information
General Information of This Linker
| Linker ID |
LIN0IXWFR
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| Linker Name |
CN119630431A-ADC-41-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C32H35N3O12S2
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| Isosmiles |
O=C(O)C[C@H](NC([C@@H](NC(CCOCCOCCN1C(C(SC2=CC=CC=C2)=C(SC3=CC=CC=C3)C1=O)=O)=O)CCC(O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C32H35N3O12S2/c36-24(33-22(11-12-25(37)38)29(41)34-23(32(44)45)19-26(39)40)13-15-46-17-18-47-16-14-35-30(42)27(48-20-7-3-1-4-8-20)28(31(35)43)49-21-9-5-2-6-10-21/h1-10,22-23H,11-19H2,(H,33,36)(H,34,41)(H,37,38)(H,39,40)(H,44,45)/t22-,23-/m0/s1
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| InChIKey |
XPORIDPQOYOCKZ-GOTSBHOMSA-N
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| Pharmaceutical Properties |
Molecule Weight
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717.775
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Polar area
|
225.94
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Complexity
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1409.447586
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xlogp Value
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1.9684
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Heavy Count
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49
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Rot Bonds
|
22
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Hbond acc
|
11
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker