Linker Information
General Information of This Linker
| Linker ID |
LIN0IWJKO
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| Linker Name |
Daratumumab-I-22--0.18 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C58H93N13O19
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| Isosmiles |
O=C(OC1=CC=C(C(NCCOCCOCCOCCOCCC(N[C@@H](CCCNC(N)=N)C(NC(C(NCC(NC(C(O)=O)CC2=CNC3=C2C=CC=C3)=O)=O)CCCNC(N)=N)=O)=O)=O)C=C1)CCOCCOCCOCCOCCOCCOCCN
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| InChI |
InChI=1S/C58H93N13O19/c59-15-21-82-25-29-86-33-36-89-38-37-88-35-32-85-28-24-81-20-14-52(74)90-44-11-9-42(10-12-44)53(75)64-18-22-83-26-30-87-34-31-84-27-23-80-19-13-50(72)69-48(8-4-17-66-58(62)63)55(77)71-47(7-3-16-65-57(60)61)54(76)68-41-51(73)70-49(56(78)79)39-43-40-67-46-6-2-1-5-45(43)46/h1-2,5-6,9-12,40,47-49,67H,3-4,7-8,13-39,41,59H2,(H,64,75)(H,68,76)(H,69,72)(H,70,73)(H,71,77)(H,78,79)(H4,60,61,65)(H4,62,63,66)/t47?,48-,49?/m0/s1
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| InChIKey |
CTFKEPBYTLFTOX-AQOSWLGISA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1276.454
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Polar area
|
467.01
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Complexity
|
2432.437083
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xlogp Value
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-1.86756
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Heavy Count
|
90
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Rot Bonds
|
55
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Hbond acc
|
21
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Hbond Donor
|
14
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Each Antibody-drug Conjugate Related to This Linker