Linker Information
General Information of This Linker
| Linker ID |
LIN0ISVCV
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| Linker Name |
CN113549127A-ADC-20-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C23H36N6O8S
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| Isosmiles |
NCCCC[C@H](NC(COCC(NCCOCCOCCCN1CC2=C(C=NC(S)=N2)C1=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C23H36N6O8S/c24-5-2-1-4-17(22(33)34)27-20(31)15-37-14-19(30)25-6-9-36-11-10-35-8-3-7-29-13-18-16(21(29)32)12-26-23(38)28-18/h12,17H,1-11,13-15,24H2,(H,25,30)(H,27,31)(H,33,34)(H,26,28,38)/t17-/m0/s1
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| InChIKey |
MSCFESMQJTXVBO-KRWDZBQOSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
556.642
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Polar area
|
195.3
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Complexity
|
881.2994281
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xlogp Value
|
-1.0244
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Heavy Count
|
38
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Rot Bonds
|
20
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Hbond acc
|
11
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker