Linker Information
General Information of This Linker
| Linker ID |
LIN0IRWSV
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| Linker Name |
Conjugate No.152 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H46N8O14
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| Isosmiles |
O=C(N1CCC(NCCOCCOCCC(N[C@@H](CCC(O)=O)C(NCC(NCC(NCC(NCC(NCCOC)=O)=O)=O)=O)=O)=O)=O)C=CC1=O
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| InChI |
InChI=1S/C30H46N8O14/c1-50-12-8-32-23(41)16-33-24(42)17-34-25(43)18-35-26(44)19-36-30(49)20(2-5-29(47)48)37-22(40)7-11-51-14-15-52-13-9-31-21(39)6-10-38-27(45)3-4-28(38)46/h3-4,20H,2,5-19H2,1H3,(H,31,39)(H,32,41)(H,33,42)(H,34,43)(H,35,44)(H,36,49)(H,37,40)(H,47,48)/t20-/m0/s1
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| InChIKey |
DGVRSCONKUVNRU-FQEVSTJZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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742.74
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Polar area
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306.07
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Complexity
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1218.383091
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xlogp Value
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-5.582
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Heavy Count
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52
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Rot Bonds
|
28
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Hbond acc
|
13
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker