Linker Information
General Information of This Linker
| Linker ID |
LIN0IRKTR
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| Linker Name |
CN116137818A-AbT-EXP10-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H32N4O12S
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| Isosmiles |
CC([C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](C)C(NC2=CC(S(O)(=O)=O)=C(C=C2)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C25H32N4O12S/c1-14(2)22(28-19(30)8-10-40-11-9-29-20(31)6-7-21(29)32)24(34)26-15(3)23(33)27-17-5-4-16(13-41-25(35)36)18(12-17)42(37,38)39/h4-7,12,14-15,22H,8-11,13H2,1-3H3,(H,26,34)(H,27,33)(H,28,30)(H,35,36)(H,37,38,39)/t15-,22-/m0/s1
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| InChIKey |
BPSRIWOQLJTKHY-NYHFZMIOSA-N
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| Pharmaceutical Properties |
Molecule Weight
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612.614
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Polar area
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234.81
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Complexity
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1281.480571
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xlogp Value
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0.0436
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Heavy Count
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42
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Rot Bonds
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15
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Hbond acc
|
10
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Hbond Donor
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5
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Each Antibody-drug Conjugate Related to This Linker