Linker Information
General Information of This Linker
| Linker ID |
LIN0IOXYC
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| Linker Name |
Linker of ADC2-61
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H46N6O12
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| Isosmiles |
CC([C@H](NC([C@@H](NC(CCCCCN1C(C=CC1=O)=O)=O)CCC(NC[C@@H](O2)[C@@H](O)[C@@H](O)[C@@H]2CC(N)=O)=O)=O)C(N[C@@H](C)C(O)=O)=O)C
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| InChI |
InChI=1S/C30H46N6O12/c1-15(2)25(29(45)33-16(3)30(46)47)35-28(44)17(34-22(39)7-5-4-6-12-36-23(40)10-11-24(36)41)8-9-21(38)32-14-19-27(43)26(42)18(48-19)13-20(31)37/h10-11,15-19,25-27,42-43H,4-9,12-14H2,1-3H3,(H2,31,37)(H,32,38)(H,33,45)(H,34,39)(H,35,44)(H,46,47)/t16-,17-,18-,19+,25-,26-,27+/m0/s1
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| InChIKey |
CSCDATAQHIWTIW-UCWDQGSZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
682.728
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Polar area
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283.86
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Complexity
|
1176.262704
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xlogp Value
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-3.0523
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Heavy Count
|
48
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Rot Bonds
|
20
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Hbond acc
|
11
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker