Linker Information
General Information of This Linker
| Linker ID |
LIN0IOENL
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| Linker Name |
Drug linker PB082
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Formula |
C61H102N6O25
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| Isosmiles |
CC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(O2)[C@H](O)[C@@H](O)C(O)[C@H]2C(O)=O)=O)C(NC3=CC=C(C=C3)CO)=O)=O)C
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| InChI |
InChI=1S/C61H102N6O25/c1-45(2)53(66-50(70)9-4-3-7-19-67-51(71)14-15-52(67)72)59(77)65-48(58(76)64-47-12-10-46(44-68)11-13-47)8-5-6-17-62-49(69)16-20-80-22-24-82-26-28-84-30-32-86-34-36-88-38-40-90-42-43-91-41-39-89-37-35-87-33-31-85-29-27-83-25-23-81-21-18-63-60-56(75)54(73)55(74)57(92-60)61(78)79/h10-15,45,48,53-57,60,63,68,73-75H,3-9,16-44H2,1-2H3,(H,62,69)(H,64,76)(H,65,77)(H,66,70)(H,78,79)/t48-,53-,54-,55?,56+,57-,60?/m0/s1
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| InChIKey |
FWNNEHMWZPMUCP-WEJURXMJSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1319.504
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Polar area
|
404.02
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Complexity
|
2078.940524
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xlogp Value
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-1.414
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Heavy Count
|
92
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Rot Bonds
|
59
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Hbond acc
|
25
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Hbond Donor
|
10
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Each Antibody-drug Conjugate Related to This Linker