Linker Information
General Information of This Linker
| Linker ID |
LIN0ILNXT
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
TW202506738A-C-327-LINKER
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C37H64N4O16
|
|||||
| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCC(NCCCC[C@@H](NC(CCCN1C(C=CC1=O)=O)=O)C(NCCCC(O)=O)=O)=O
|
|||||
| InChI |
InChI=1S/C37H64N4O16/c1-49-14-15-50-16-17-51-18-19-52-20-21-53-22-23-54-24-25-55-26-27-56-28-29-57-30-33(43)38-11-3-2-6-31(37(48)39-12-4-8-36(46)47)40-32(42)7-5-13-41-34(44)9-10-35(41)45/h9-10,31H,2-8,11-30H2,1H3,(H,38,43)(H,39,48)(H,40,42)(H,46,47)/t31-/m1/s1
|
|||||
| InChIKey |
AHPLQULBCOUAES-WJOKGBTCSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
820.931
|
Polar area
|
245.05
|
||
|
Complexity
|
1059.317538
|
xlogp Value
|
-0.7769
|
|||
|
Heavy Count
|
57
|
Rot Bonds
|
41
|
|||
|
Hbond acc
|
15
|
Hbond Donor
|
4
|
|||
Each Antibody-drug Conjugate Related to This Linker