Linker Information
General Information of This Linker
| Linker ID |
LIN0IKKVZ
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| Linker Name |
Anti-Her2-AL1- LP3 LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C26H44N8O10
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| Isosmiles |
O=C(NCC(NCC(NCC(O)=O)=O)=O)CNC(COC1CC(N=NN2CCOCCOCCOCCN)=C2CCCC1)=O
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| InChI |
InChI=1S/C26H44N8O10/c27-5-7-41-9-11-43-12-10-42-8-6-34-21-4-2-1-3-19(13-20(21)32-33-34)44-18-25(38)30-16-23(36)28-14-22(35)29-15-24(37)31-17-26(39)40/h19H,1-18,27H2,(H,28,36)(H,29,35)(H,30,38)(H,31,37)(H,39,40)
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| InChIKey |
NKPLKNOBHFXMLV-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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628.684
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Polar area
|
247.35
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Complexity
|
993.2284914
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xlogp Value
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-3.5099
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Heavy Count
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44
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Rot Bonds
|
22
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Hbond acc
|
13
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker