Linker Information
General Information of This Linker
| Linker ID |
LIN0IJDKC
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| Linker Name |
P5 (PEG2)- VC-PAB linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C32H45N6O11PS
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| Isosmiles |
CC(C(NC(C1=CC=C(NP(/C=C\S)(OCCOCCO)=O)C=C1)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(O)=O)C=C2)=O)=O)C
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| InChI |
InChI=1S/C32H45N6O11PS/c1-21(2)27(37-28(40)23-7-11-25(12-8-23)38-50(46,18-19-51)49-17-16-47-15-14-39)30(42)36-26(4-3-13-34-31(33)43)29(41)35-24-9-5-22(6-10-24)20-48-32(44)45/h5-12,18-19,21,26-27,39,51H,3-4,13-17,20H2,1-2H3,(H,35,41)(H,36,42)(H,37,40)(H,38,46)(H,44,45)(H3,33,34,43)/b19-18-/t26-,27?,50?/m0/s1
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| InChIKey |
ZNMVCJWQZPJBMN-ZQEUGTQBSA-N
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| Pharmaceutical Properties |
Molecule Weight
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752.784
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Polar area
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256.74
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Complexity
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1450.88665
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xlogp Value
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3.2391
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Heavy Count
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51
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Rot Bonds
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22
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Hbond acc
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11
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Hbond Donor
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9
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Each Antibody-drug Conjugate Related to This Linker