Linker Information
General Information of This Linker
| Linker ID |
LIN0IJDCZ
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|---|---|---|---|---|---|---|
| Name |
Mal-PEG4-Val-Lys (PEG16)-Cit-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C54H91N7O28
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| Isosmiles |
CC(C)[C@@H](C(N[C@H](C(NC1=CC=C(C=C1)CO)=O)CCCNC(NCCOCOCOCOCOCOCOCOCOCOCOCOCOCOCOCOC)=O)=O)NC(CCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O
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| InChI |
InChI=1S/C54H91N7O28/c1-43(2)51(60-48(64)13-18-71-21-23-73-25-26-74-24-22-72-19-15-55-47(63)12-17-61-49(65)10-11-50(61)66)53(68)59-46(52(67)58-45-8-6-44(27-62)7-9-45)5-4-14-56-54(69)57-16-20-75-29-77-31-79-33-81-35-83-37-85-39-87-41-89-42-88-40-86-38-84-36-82-34-80-32-78-30-76-28-70-3/h6-11,43,46,51,62H,4-5,12-42H2,1-3H3,(H,55,63)(H,58,67)(H,59,68)(H,60,64)(H2,56,57,69)/t46-,51-/m0/s1
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| InChIKey |
YACHOBAZAJAPAJ-YWHGXOANSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1286.343
|
Polar area
|
399.74
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Complexity
|
1906.543972
|
xlogp Value
|
-1.0319
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Heavy Count
|
89
|
Rot Bonds
|
62
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Hbond acc
|
28
|
Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker