Linker Information
General Information of This Linker
| Linker ID |
LIN0IHRTT
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|---|---|---|---|---|---|---|
| Linker Name |
DBCO-nAA-PEG4
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C41H53N3O9
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| Isosmiles |
O=C(N(CC1)CCC1(CC2)CCC2C(NCCC(N3CC4=C(C#CC5=C3C=CC=C5)C=CC=C4)=O)=O)CCOCCOCCOCCOCCC(O)=O
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| InChI |
InChI=1S/C41H53N3O9/c45-37(14-23-50-25-27-52-29-30-53-28-26-51-24-15-39(47)48)43-21-18-41(19-22-43)16-11-34(12-17-41)40(49)42-20-13-38(46)44-31-35-7-2-1-5-32(35)9-10-33-6-3-4-8-36(33)44/h1-8,34H,11-31H2,(H,42,49)(H,47,48)
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| InChIKey |
VVSVZKBPCWBZGL-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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731.887
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Polar area
|
143.94
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Complexity
|
1533.476964
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xlogp Value
|
4.1695
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Heavy Count
|
53
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Rot Bonds
|
19
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Hbond acc
|
8
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker