Linker Information
General Information of This Linker
| Linker ID |
LIN0ICFZO
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| Linker Name |
Anti-Her2-LP16 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C48H81N11O15
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| Isosmiles |
NCCOCCOCCOCCN(N=N1)C2=C1CC(NCCOCCOCCOCCOCCC(N[C@H](C(N[C@@H](CCCNC(N)=O)C(NC3=CC=C(C=C3)COC(NCC(O)=O)=O)=O)=O)C(C)C)=O)CCCC2
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| InChI |
InChI=1S/C48H81N11O15/c1-35(2)44(46(64)55-39(7-5-15-52-47(50)65)45(63)54-37-11-9-36(10-12-37)34-74-48(66)53-33-43(61)62)56-42(60)13-18-67-22-26-71-30-31-73-28-24-69-20-16-51-38-6-3-4-8-41-40(32-38)57-58-59(41)17-21-70-25-29-72-27-23-68-19-14-49/h9-12,35,38-39,44,51H,3-8,13-34,49H2,1-2H3,(H,53,66)(H,54,63)(H,55,64)(H,56,60)(H,61,62)(H3,50,52,65)/t38?,39-,44-/m0/s1
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| InChIKey |
PMHRBOZZBQMYQD-NRQMKXBWSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1052.238
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Polar area
|
351.42
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Complexity
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1816.441824
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xlogp Value
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-0.0062
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Heavy Count
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74
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Rot Bonds
|
41
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Hbond acc
|
19
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker