Linker Information
General Information of This Linker
| Linker ID |
LIN0HWHGL
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| Linker Name |
Mc-PEG4-VK-PABC
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C50H74N8O12
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| Isosmiles |
CC([C@H](NC(CCOCCOCCOCCOCCNC(COC1C2=C(CCCCC1)C(C(C=C3)=CC=C3CN)=NN=C2C)=O)=O)C(N[C@@H](CCCCN)C(NC4=CC=C(C=C4)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C50H74N8O12/c1-34(2)46(49(62)55-41(10-7-8-21-51)48(61)54-39-18-14-37(15-19-39)32-70-50(63)64)56-43(59)20-23-65-25-27-67-29-30-68-28-26-66-24-22-53-44(60)33-69-42-11-6-4-5-9-40-45(42)35(3)57-58-47(40)38-16-12-36(31-52)13-17-38/h12-19,34,41-42,46H,4-11,20-33,51-52H2,1-3H3,(H,53,60)(H,54,61)(H,55,62)(H,56,59)(H,63,64)/t41-,42?,46-/m0/s1
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| InChIKey |
CREMNOAWWPRMGY-BEGJAILCSA-N
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| Pharmaceutical Properties |
Molecule Weight
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979.186
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Polar area
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286.9
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Complexity
|
1978.116
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xlogp Value
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4.24552
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Heavy Count
|
70
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Rot Bonds
|
32
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Hbond acc
|
15
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker